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How do you approach CNS prophylaxis in double-hit lymphoma patients?
Do you only give intrathecal chemotherapy or systemic therapy?
Answer from: Medical Oncologist at Academic Institution
There is no consensus about the need for IT chemo for CNS prophylaxis in DLBCL. Factors such as IPI, the number and location of extranodal sites of disease, and LDH may be used to identify a group of patients with aggressive NHL who are at particularly high risk for CNS recurrence and might therefor...
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