How do you approach early stage, mixed histology lung cancer (SCLC and NSCLC components) in patients with good performance status?
Is there a role for surgery? Assume early stage with negative nodes on EBUS and PET.
Answer from: Radiation Oncologist at Academic Institution
Certainly the simplest approach for an early stage mixed SCLC/NSCLC would be upfront surgical resection and node dissection (provided that good performance status implies medical operability), and then pathologically if a true small cell component is confirmed (or if the patient is found to be node ...
Answer from: Medical Oncologist at Community Practice
We published our experience (Babakoohi et al. Clinical Lung Cancer 2013) with combined small cell carcinoma (meaning both a small cell and non-small cell component). In over 400 patients with small cell we found 22 patients with combined small cell. The outcome of combined small cell is overall bett...