How do you approach the initial dosing of carfilzomib for patients with relapsed multiple myeloma?
Is the therapeutic purpose of the proteasome inhibitor to maximize total dosage per week or number of infusions per week?
Answer from: Medical Oncologist at Academic Institution
A great question and one without a uniform answer! I place a lot of focus on patient quality of life, and one of the recurring themes from patients is the number of visits to the medical center. A twice-weekly regimen of carfilzomib (or bortezomib for that matter), over the course of a year, re...
Comments
Medical Oncologist at Los Angeles VA Medical Center Dr. @Ben Derman, how do you dose carfilzomib in re...
Medical Oncologist at University of Chicago If it is a deep response (i.e. CR), and at least 8...
Answer from: Medical Oncologist at Academic Institution
Could not agree more with Dr. @Ben Derman. "Home time" is tremendously important to our patients, and the efficacy bar to default to twice-weekly carfilzomib should be quite high to justify its use. As two quick additions to his expert comments:
We will someday have an answer about twice-weekly 27m...
Dr. @Ben Derman, how do you dose carfilzomib in re...
If it is a deep response (i.e. CR), and at least 8...