How do you approach the management of an early stage non-small cell lung cancer limited to an endobronchial location (non-obstructing) in a patient that is not considered operable due to medical comorbidities?  

The use of SBRT is predicated on CT based imaging so that a physical and visible target can be delineated and for which a radiotherapy plan can be generated. For patients where no such imaging-definable lesion has been identified, as with for example, an endobronchial-only lesion noted at the time o...

Generally, favor concurrent chemoradiation to 60 Gy in 30 fractions in these cases particularly if we are talking about the involvement of proximal bronchial tree due to concern for bronchial necrosis and hemorrhage as detailed by Dr. @Moghanaki above. I do frequently utilize SBRT-like hypofractiona...

We are all aware of the enthusiasm for SBRT in early stage lung cancer. But, if it's because we think it is more likely to help our patients live a long time, then we must always be mindful about the risks of late effects. Once the cartilaginous structures of the bronchus necrose, bad things can hap...

We have implanted many tracheal and paratracheal malignant lesions with ct-guided permanent seed brachytherapy and have not seen necrosis even in patients who had salvage implant following failed external beam, documented by repeated bronchoscopies.CT-guided permanent seed brachytherapy is a simple ...