How do you approach the treatment of breast cancer with enlarged but indeterminate breast nodes?

For a cT2 triple negative breast cancer with indeterminate enlarged breast nodes s/p negative biopsies, and indeterminate findings on both MRI and PET/CT, would you consider excisional biopsy, or upfront resection rather than pre-op chemo?

Answer from: Radiation Oncologist at Community Practice

Since T2 no, pre-op chemo plus IO and then surgery which would involve SNLN plus removal of targeted node (even though negative would add clip at biopsy).

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How do you approach the treatment of breast cancer with enlarged but indeterminate breast nodes?

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