How do you approach treatment of a grade 4 IDH-mutant astrocytoma, a diagnosis now distinct from glioblastoma according to the 2021 WHO Classification for CNS Tumors?
Answer from: Medical Oncologist at Community Practice
This is an excellent question. The short answer is that until we have more data on this new entity, I would treat an IDH mutant (mt) grade 4 astrocytoma as I would have prior to the 2021 WHO revision, that is to say, with concurrent chemoradiation therapy and adjuvant Temodar for 6 cycles (or a clin...
Comments
Medical Oncologist at ProMedica Flower Hospital @Nicole A. Shonka would you also utilize tumo...
Medical Oncologist at Locum Tenens Great review and insight!
Medical Oncologist at Nebraska Medcal Center Hi Dr. @Macari,
Based on the criteria for inclusi...
Radiation Oncologist at University of Missouri at Columbia, Ellis Fischel Cancer Cener About 5% of the tumors on EF-14 had IDH mutations,...
@Nicole A. Shonka would you also utilize tumo...
Great review and insight!
Hi Dr. @Macari, Based on the criteria for inclusi...
About 5% of the tumors on EF-14 had IDH mutations,...