How do you choose between neoadjuvant chemotherapy alone vs neoadjuvant chemoradiation in patients with potentially resectable stage III NSCLC who are not upfront surgical candidates?   

Stage III disease is always a challenging situation. Thoracic surgery assessment is key in deciding about the role of radiation as it may impact surgery. Induction chemotherapy has demonstrated efficacy in multiple studies (including a meta-analysis Berghmans et al 2005). If pneumonectomy is a possi...