How do you compensate for treatment breaks >1 week in patients with NSCLC on concurrent chemoradiation?

Do you use BID treatments toward the end? Do you add additional daily treatments to exceed the prescription dose? Would you alter systemic therapy dose or scheduling?

Answer from: Radiation Oncologist at Community Practice

Classical radiobiology dictates that some sort of treatment intensification could be indicated for a locally advanced NSCLC patient whose chemoradiotherapy course is interrupted. Though many of my patients have treatment interruptions for a variety of reasons, I almost never increase the total presc...

Comments

Radiation Oncologist at UCLA | VA Greater Los Angeles Healthcare System
I agree with @Nitin Ohri, especially the 2nd bulle...

Radiation Oncologist at UNC School of Medicine
I largely agree with @Nitin Ohri. (1) If the brea...

Answer from: Radiation Oncologist at Community Practice

No treatment break is preferred, without escalating the total dose.

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How do you compensate for treatment breaks >1 week in patients with NSCLC on concurrent chemoradiation?

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