How do you decide between re-irradiation, chemotherapy, and alternating electric field therapy in patients with relapsed GBM post chemoradiation with TMZ?
If choosing systemic therapy, do you prefer bevacizumab with or without irinotecan? Have you used anti-PD1 agents (e.g. nivolumab) off label?
Answer from: Medical Oncologist at Academic Institution
The best care for patients with glioblastoma is multi-disciplinary. For that reason, we review these patients in our tumor board. The critical questions are - 1) Is this truly disease progression or could it be radiation necrosis/ pseudoprogression? 2) What functions are located in the area of recur...