How do you decide when to use andexanet (ANDEXXA) for intracranial hemorrhage associated with factor Xa inhibitors?

In light of ANNEXA-I RCT results: Connolly et al., PMID 38749032.

Answer from: at Community Practice

The ANNEXA-I trial presents a mixed perspective. The data demonstrated that Andexanet is superior to standard care in reducing hematoma expansion for intracerebral hemorrhage associated with factor Xa inhibitors. This conclusion is based on an imaging-based primary endpoint, supported by previous st...

Comments

at Lourdes Medical Center Burlington
Data leaves decision open.

at University of Colorado, Climate & Health Dept
I agree, poor evidence that it improves clinical o...

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How do you decide when to use andexanet (ANDEXXA) for intracranial hemorrhage associated with factor Xa inhibitors?

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