How do you dose oral tranexamic acid for melasma?

Given the side effect profile and risk of relapse off oral TXA therapy, do you prefer pulse dosing (i.e., 3 months on, 3 months off) or continuous therapy at the lowest effective dose?

Answer from: at Academic Institution

I typically do 325 mg BID (1/2 tab of 650mg) during May-Sept then off in the winter. Double layer of sunscreen: chemical then mineral over it. Two favorites are La Roche Posay Cooling Water Lotion SPF60 then Eucerin Sensitive Mineral Agave SPF35 over that every morning regardless of the days activit...

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at Complete Skin Care at Steil Dermatology
Hi, I've always thought you should not mix a miner...

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How do you dose oral tranexamic acid for melasma?

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