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Topics:
Radiation Oncology • Gastrointestinal Cancers • Medical Oncology • Liver and Pancreas Tumors • Internal Medicine • Hepatocellular Carcinoma • Gastroenterology • General Hepatology
How do you employ focal therapies in localized hepatocellular carcinoma?
Will the results of the recently published randomized comparison of proton beam therapy (PBT) vs. transarterial chemoembolization (TACE) change the way that you manage hepatocellular carcinoma?
Answer from: Radiation Oncologist at Academic Institution
Great question – I think this trial provides some pretty interesting insights, even though it failed to meet its primary endpoint. To summarize, this was a randomized phase 3 clinical trial that included patients with newly diagnosed and untreated hepatocellular carcinoma (HCC) within Mil...
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Answer from: Radiation Oncologist at Academic Institution
This is not a practice-changing trial but helps inform treatment discussions.Most patients on this trial (with mean tumor size of 3.2 cm) who are treated with external beam radiation will continue to be treated with SBRT (or TACE followed by SBRT). SBRT is a much more straightforward and available t...