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Topics:
Breast Cancer • Medical Oncology
How do you manage aromatase inhibitor- associated musculoskeletal syndrome (AIMSS) symptoms in post-menopausal breast cancer patients?
Does switching AIs help? If so, is there a role for switching from a steroidal AI to a non-steroidal AI or vice versa? Are there other adjunctive treatments that should be tried before switching therapies?
Answer from: Medical Oncologist at Academic Institution
Available published data suggests that switching from one AI to another, does help to reduce AIMSS. This strategy is associated with improvement in AIMSS about 50% of the time (in published literature). From personal experience, letrozole tends to cause the most symptoms since from pharm...
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Answer from: Medical Oncologist at Community Practice
I have luck with the use of Vitamin D , chondroitin sulfate and Glucosamine in some patients.