How do you manage endocrine therapy for a perimenopausal woman with ER+ breast CA?

The woman was on on a GnRH agonist + AI due to her premenopausal status at diagnosis and now wants to know if she continues to need the GnRH agonist.

Answer from: Medical Oncologist at Academic Institution

In lower risk patients to whom I would not routinely give chemotherapy - stage I-IIA, with a low or low-intermediate risk Oncotype score - I start tamoxifen and switch to an aromatase inhibitor (except in very low risk patients in whom the benefit of switching would be negligible) when the...

Comments

Medical Oncologist at University of Wisconsin School of Medicine and Public Health
Agree with the above - monitoring is the key! Some...

Medical Oncologist at Perlmutter Cancer Center of NYU Langone Health
Thank you for your response. Can you comment on if...

Medical Oncologist at Cleveland Clinic
Do you hold tamoxifen prior to checking estradiol ...

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How do you manage endocrine therapy for a perimenopausal woman with ER+ breast CA?

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