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Topics:
Thoracic Malignancies
•
Medical Oncology
How do you transition between TKIs for stage IV NSCLC with actionable mutations?
Do you prefer a washout period or overlap period? Does your approach differ with different TKIs?
Related Questions
What is your preferred treatment option after tarlatamab for patients with ES-SCLC?
Would you offer tarlatamab to patients with metastatic EGFR+ NSCLC that transformed into SCLC?
How would you treat patient with a stage IV lung adenocarcinoma, an exon 21 p.H835L mutation, high TMB, and negative PD-L1?
Are you using maintenance lurbinectedin with immunotherapy in the first-line treatment of extensive stage small cell lung cancer?
How would you manage a patient with metastatic NSCLC and high-level MET amplification who achieved a near CR on tepotinib but is unable to tolerate dose-reduced tepotinib?
How would you treat a patient with metastatic NSCLC, adenocarcinoma subtype with BRAF V600K mutation, PD-L1 >50% with progression on 1st line chemo-immunotherapy?
Is there any data on the safety or efficacy of combining osimertinib-based therapy with HER2-targeted treatment in patients with EGFR-mutant NSCLC and concurrent HER2-positive breast cancer?
In light of the 2024 Shkreli Awards, how do you address patient concerns regarding the 240 mg versus 960 mg dose of sotorasib?
Is there any data supporting the use of osimertinib in patients with L858R-mutated lung cancer who had a durable response to prior EGFR TKI therapy, and who progressed 1-2 years after discontinuation of other EGFR inhibitors?
Would you continue tarlatamab in CNS-only progression of small cell cancer if there is no systemic disease?