How do you treat episodes of profuse sweating in Parkinson’s patients?  

By far most common situation is OFF-related hyperhidrosis, such as overnight OFF, and so this needs to be explored with patients paying close attention to when these things tend to happen and whether they correlate with motor worsening; trials of dopaminergic dose alterations could be considered and...

This is a difficult problem and can occur during on or off episodes. I recommend wearing linen, keeping a change of clothing and using fans whenever possible. There are also cooling gadgets. Sometimes, at bedtime I might give gabapentin. Others have tried propranolol.

In addition to the recommendations of Dr. @Beach, botulinum toxin injections can be effective in some patients with: 1) focal hyperhidrosis or 2) when the hyperhidrosis begins at some well-defined areas. For example, patients may experience excessive sweating at the posterior neck or at the scalp th...