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Radiation Oncology • Gastrointestinal Cancers
How do you treat localized esophageal carcinoma in patients who are unwilling or unable to undergo chemotherapy or surgery?
If a patient is unable or unwillling to undergo dual or tri-modality therapy with chemotherapy or surgery, would you use a palliative radiation treatment dose or would you try to treat to higher dose (>50 Gy) despite lack of evidence for dose escalation benefit?
Answer from: Radiation Oncologist at Academic Institution
This is a question that comes up occasionally in clinic. My viewpoint is generally based on the prospective data that we have. Of course, the RTOG 85-01 study showed 0% long-term OS with definitive RT vs CRT. Additionally, the Intergroup 0123 study showed no evidence of improvement with higher dose...
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