How do you treat patients rendered NED after resection of an isolated lung recurrence of an early stage triple negative breast CA years after adjuvant chemotherapy?  

While such patient is at high risk for a subsequent recurrence of metastatic disease, there is no data to suggest that administering 'adjuvant' chemotherapy following resection of a solitary metastasis will improve disease-free or overall survival and thus I would simply continue to observe the pati...

I preferentially give neoadjuvant therapy before resection. Theoretically, this patient is eligible for atezolizumab and nab-paclitaxel if PDL1 positive (1% or greater). The benefit of a solitary site removal, regardless of time delay in triple-negative, should not be translated as real into al...