How does your surveillance for DLBCL change given the new role of CAR-T in 2nd line treatment?
How do you assess if a patient may be a candidate for CAR-T cell therapy?
Answer from: Medical Oncologist at Academic Institution
There were at least 2 large studies from Europe showing that surveillance imaging for lymphoma patients in remission after completion of upfront treatments don’t improve survival (regardless of histology). I don’t usually get any imaging for DLBCL in remission after the end of treatment ...
Answer from: Medical Oncologist at Academic Institution
Our surveillance has not changed. Patients are assessed with end of front line treatment imaging, clinically followed every 3 months, and radiographically followed every 6 months for the first two years. If new or progressive disease is found, we would biopsy for disease confirmation and then evalua...
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Medical Oncologist at University of Maryland Cancer Center I agree. Having said that, one will need to rememb...
Answer from: Medical Oncologist at Academic Institution
Surveillance practices have not changed at this time. Patients are assessed for CAR T-cell therapy based on their eligibility from a disease perspective (number of lines of therapy, primary refractoriness, or early relapsed) and based on medical co-morbidities. Age is considered but not the only det...