How strongly you would recommend surgery in case of distal squamous cell esophageal cancer who completed chemo/RT and achieved CR?
Especially if the patient had advanced N3 disease and is reluctant to pursue surgery?
Answer from: Medical Oncologist at Academic Institution
This scenario presents a number of competing concerns. In general, the practice of our group is to consider observation for patients who achieve a clinical complete response (cCR) to chemoradiation, based on 2 European studies that show no clear improvement in OS for esophagectomy in patients with e...