How would treat recurrent, unresectable thymoma in patients treated previously with CAP and radiation therapy with long interval to recurrence (>2 years)?  

There are a host of single agents that have activity in thymoma, but unfortunately, none are curative. As such, my approach is to use single agents one at a time to create a more durable chronic disease and to minimize toxicity that is often seen with combination therapy. So drugs with activity incl...