How would you approach a locally recurrent, unresectable (due to COPD) NSCLC that is ROS1 positive?

Would you treat with localized therapy with chemoradiation or SBRT or consider ROS-1 directed therapies?

Answer from: Medical Oncologist at Academic Institution

It depends on extent of disease, pattern of recurrence. Is this a recurrence post resection? Did the patient receive adjuvant chemotherapy previously? Is it limited to mediastinum? If the patient qualifies for chemotherapy and radiation i would consider it. If he/she do not qualify due to extent of ...

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Medical Oncologist at Center for Hematology and Oncology
We are talking about a small recurrence in the sit...

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How would you approach a locally recurrent, unresectable (due to COPD) NSCLC that is ROS1 positive?

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