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Please select the option that best describes you:
Topics:
Rheumatology
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Antiphospholipid Syndrome
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Systemic lupus erythematosus
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Benign Hematology
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Anticoagulation
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Hospital Medicine
How would you approach a patient with SLE and catastrophic antiphospholipid antibody system that has not responded to heparin, steroids, and PLEX?
How do you decide amongst other therapies such as eculizumab, rituximab, cyclophosphamide, IVIg?
Related Questions
How would you work up splenomegaly and abdominal pain in a patient with primary antiphospholipid syndrome and a high + ANA, but no other serological or clinical SLE symptoms?
How do you manage patients with positive antiphospholipid antibodies in the perioperative setting for solid organ transplant, such as renal transplant?
Do you hospitalize patients with newly diagnosed lupus nephritis and nephrotic syndrome if you are able to provide pulse steroids outpatient and follow them closely?
In patients with lupus nephritis, and MAHA with positive anti-phospholipid autoantibodies, what are the considerations to use or not use anti-coagulation therapy?
Can anti-cardiolipin or anti-beta-2 glycoprotein antibodies cause prolonged PTT in the absence of a lupus anticoagulant?
How often should lupus anticoagulant be checked in patients with SLE if prior was negative or if prior was positive?
For patients with SLE, is there an ANC level for which you would hold or adjust hydroxychloroquine in an asymptomatic patient?
What is your threshold to repeat a kidney biopsy in a patient with a history of lupus nephritis who is on maintenance therapy and develops subtle changes in urinary protein excretion or microscopic hematuria?
How would you approach a patient with class III and V lupus nephritis, already on HCQ, MMF, voclosporin and losartan, but has continued proteinuria not yet attaining complete renal response?
How would you approach the evaluation and management of isolated vasculitis with aneurysms involving the segmental hepatic arteries causing hepatic hemorrhage in an otherwise healthy patient in his 80s?