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How would you approach a post-menopausal women with recurrent ER/PR+, HER2- breast cancer only in the axillary lymph nodes?
< 4 lymph nodes involved, initial diagnosis was 11 years ago when she was treated with mastectomy and adjuvant tamoxifen for 5 years.
Answer from: Medical Oncologist at Academic Institution
Patients who relapse more than 10 years after diagnosis have a particularly favorable course. She has an endocrine-sensitive disease just by the criteria of long disease-free survival. For example, in S0226 in a subset of patients who relapsed more than 10 years after initial diagnosis, we saw ...
Answer from: Medical Oncologist at Academic Institution
If not done already, I would make sure to obtain staging scans to ensure recurrence is limited to the ALN. Would refer to surgery for resection of the nodes and full ALND if not done before, and to radiation oncology for consideration of RT (assuming she has not received it before). Given she has a ...
Answer from: Medical Oncologist at Community Practice
ALND. RT. Anastrozole
Answer from: Medical Oncologist at Community Practice
Initially PET/CT to evaluate metastases.Then chemotherapy (CALOR trial), followed by local treatment.
If she is elderly, agree, particularly with possib...