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How would you approach the decision to escalate DMT in a patient with relapsing multiple sclerosis who has two to three new T2 lesion but no clinical symptoms?

In light of recent publication by Bsteh et al., PMID 39197111 that examined the outcomes in the treatment of RMS based on isolated MRI findings.

Answer from: at Academic Institution

I would escalate to higher-efficacy DMT in this scenario. As highlighted in the linked article, new T2 lesions show that the patient is at heightened risk for clinical relapses and their disease activity is not well controlled. In the linked study, included patients were on low efficacy DMT (interfe...

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at Neurology Associates Neuroscience Center
I agree.

Please select the option that best describes you:

How would you approach the decision to escalate DMT in a patient with relapsing multiple sclerosis who has two to three new T2 lesion but no clinical symptoms?

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