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Topics:
Rheumatology
•
Myositis
How would you approach the management of TIF-1 Gamma- associated dermatomyositis with extensive skin disease with a recent history of recurrent melanoma of skin?
Related Questions
How do you go about switching from one DMARD to another In patients with dermatomyositis that remains active?
What immunosuppressant will you choose in a patient with necrotizing myopathy partially responding to IV steroids and IVIGs with a history of non Hodgkins lymphoma?
How do you approach weakly positive PL-7 antibody in a patient who initially presented with muscle weakness, rhabdomyolysis and non specific muscular edema on MRI that resolved with IV fluids?
Do you pursue a malignancy workup beyond age-appropriate malignancy screening in patients with antibody negative necrotizing myopathy?
How do you interpret negative HMGCR antibody test results in a patient with necrotizing myopathy who has already been on treatment with steroids and whose CK has normalized?
Should IVIg dosing in patients with autoimmune disease (ie dermatomyositis) who become pregnant continue to be based on actual weight at the time of each infusion, or should it be limited at pre-pregnancy weight?
How would you approach a young patient with bilateral lower extremity muscle weakness and positive anti-Smith, dsDNA, RNP, Raynaud’s, and pericardial effusion but normal muscle enzymes?
In light of the RECITAL study, would rituximab be a reasonable choice in a patient with PL-12 antibodies, rapidly progressive pulmonary disease with organizing pneumonia on biopsy?
What would be your approach to a patient with Scleroderma/Myositis overlap syndrome (+anti-Ku) and active inflammatory eye disease despite high dose mycophenolate?
How long do you maintain patients with anti-synthetase syndrome on Rituximab?
