How would you approach therapy for newly diagnosed germinal-center DLBCL who previously received an unknown systemic regimen with radiation for history of Hodgkin Lymphoma?   

A lot of times, you can ask the patient if they received a red medication (doxorubicin) or if their hair fell out to determine prior anthracycline exposure. If you cannot confirm, I would assume that they received ABVD x 6 cycles. This would be a cumulative drug exposure of 300 mg/m^2. Depending on ...