How would you manage a ER/PR positive, HER2-negative grade 2 T3N0 invasive breast cancer s/p adjuvant chemotherapy who had post-operative complications with reconstruction?

The patient is a woman in her 30s with a grade 2 T3N0 ER/PR+ Her2- invasive ductal carcinoma who was treated with mastectomy (margin negative, but LVI positive) and adjuvant chemotherapy, and is now on hormone therapy. Her RT consult was delayed due to complications.

Would you still offer PMRT in this case?

Answer from: Radiation Oncologist at Academic Institution

The role of PMRT for pathologic T3N0 cancers remains controversial. However, I would consider PMRT for a woman in her 30s with T3N0 disease with LVSI. In terms of delay, would depend on how long since surgery and if the patient was receiving chemotherapy during that time. Literature has used differ...

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How would you manage a ER/PR positive, HER2-negative grade 2 T3N0 invasive breast cancer s/p adjuvant chemotherapy who had post-operative complications with reconstruction?

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