How would you manage a patient with a solitary plasmacytoma with a partial response to RT?   

A solitary osseous plasmacytoma can be higher or lower risk than an extra medullary plasmacytoma; for instance, a tonsillar plasmacytoma is different than one in lung parenchyma.  The largest study I know about evaluating solitary plasmacytoma of the bone involved 206 patients without evidence ...

If there was no elevation to begin with a serum light chain ratio or serum in the globulins, I would observe, but if there was an initial elevation of these with appearance of the plasmacytoma and partial reduction of those values along with partial shrinkage of the lesion, I would consider a surgic...