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Radiation Oncology • Pediatric Cancers
How would you manage adjuvant therapy in a gross totally resected favorable site embryonal RMS with resected positive lymph nodes?
For a stage I, favorable site, group IIb (LN+) embryonal RMS where both the primary and LN have been gross totally resected (margins negative), can radiation volume be limited to the involved lymph node chain, thus excluding the primary postop bed?
i.e. for para-testicular or non-parameningeal H&N primary sites
Answer from: Radiation Oncologist at Academic Institution
The paratesticular site may be different and I think controversial.
At ASTRO 2020, St. Jude/Dr. @Matthew Krasin presented results from its phase 2 trial on RMS in which they did not deliver adjuvant RT to the primary site in which a DPE was performed with negative margins and the control appeared g...
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