How would you manage an in-field small volume recurrence of early-stage favorable Hodgkin Lymphoma treated previously with 2 cycles of ABVD and 20Gy?  

An established and extremely successful treatment paradigm for early-stage favorable HL is 2 cycles of ABVD followed by 20 Gy of RT. Assuming the patient is PET negative after chemotherapy, 5-year PFS is expected to be ~93-94% based on HD16. Most recurrences after combined modality therapy (CMT) in ...

I agree with Dr. @Christopher R. Kelsey that the lion’s share of patients who relapse after combined modality treatment should proceed with salvage chemotherapy and ASCT if fit. I would add that it’s important to recognize that patients with early stage favorable HL who relapse after 2 ...