How would you manage metastatic small cell/neuroendocrine bladder cancer after response to 6 cycles of platinum/etoposide?

If any clinical benefit (ie. CR, PR or SD) would you consider switch maintenance avelumab, surveillance until progression, or an alternate regimen?

Answer from: Medical Oncologist at Community Practice

I would consider maintenance avelumab in patients with metastatic small cell carcinoma of the bladder achieving stable or responding disease after platinum-etoposide. Notably, the JAVELIN Bladder-100 trial that led to the approval of maintenance avelumab included urothelial carcinoma and not predomi...

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Medical Oncologist at University of Washington School of Medicine
Excellent and thoughtful response by @Guru P. Sonp...

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How would you manage metastatic small cell/neuroendocrine bladder cancer after response to 6 cycles of platinum/etoposide?

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