How would you manage T4N0 NSCLC with two separate nodules in different ipsilateral lobes?   

If there is no lymph node involvement and the two lesions are amendable by SABR, I would TX definitive with SABR for curative intent. The role of adjuvant TX is debatable, depending on molecular profiling and PD-L1 expression level. If not SABR, hypo-fractionated RT or concurrent chemo/RT could be c...