How would you reconcile EQD2 calculation for organs at risk in patients receiving BID fractionation to the chest after an initial course of daily conventional fractionation?

E.g treating and SCLC after prior NSCLC.

Answer from: Radiation Oncologist at Community Practice

There is a paper regarding time-based corrections to BED for hyperfractionation in such a scenario. You end up multiplying the usual result by a time factor that increases the BED above the usual daily fraction result. I don't have the reference handy but it is out there. Maybe someone else on this ...

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Radiation Oncologist at Washington University/Barnes-Jewish Hospital
I think the time adjusted-BED formulas that were u...

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How would you reconcile EQD2 calculation for organs at risk in patients receiving BID fractionation to the chest after an initial course of daily conventional fractionation?

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