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Hematologic Malignancies • Pediatric Hematology/Oncology • Medical Oncology • Lymphoma • NCI-CCC Tumor Board Question • Internal Medicine • AYA • Hematology • NCI-CCC Lymphoma Tumor Board Question • City of Hope
How would you treat a patient with Hodgkin lymphoma who has an isolated relapse within the CNS?
Answer from: Medical Oncologist at Academic Institution
It's challenging to offer specific advice in this situation without knowing a lot more. First, it's important to recognize that CNS involvement by classical Hodgkin lymphoma is extremely rare and strictly requires a brain biopsy to make a diagnosis (even in a patient with active systemic CHL, a seco...
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Answer from: Medical Oncologist at Community Practice
I agree that a CNS biopsy would be essential. If relapse is truly restricted to CNS then ICE would be an option as might stereotactic radiation therapy.