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How would you treat a patient with small cell ca of the appendix with no evidence of distant mets?
PDL1 is > 50%. There was no perforation or lymph node involvement.
Answer from: Medical Oncologist at Academic Institution
Small cell carcinomas of the appendix are exceedingly rare and one has to question if that truly is the origin of the tumor. High-grade neuroendocrine carcinoma, including both small-cell and large-cell, is much more commonly seen in the large bowel, often in the cecum.There are extremely limi...
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Answer from: Medical Oncologist at Community Practice
I agree. Small cell or high grade neuroendocrine carcinoma has a high propensity of metastases, adjuvant platinum based chemotherapy to improve survival.