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Head and Neck Cancers • Radiation Oncology
How would you treat a pt with cT2N0M0 SCC of the supraglottic larynx (good PS, swallowing function) with a bulky primary tumor?
Older data suggests that local control with RT alone for supraglottic tumors >6cc is fairly low.
Would you employ altered fractionation (what dose/fractionation?) and/or concurrent chemotherapy?
Answer from: Radiation Oncologist at Academic Institution
The University of Florida data suggests that bulky supraglottic larynx cancer >6 cc have relatively poor local control following standard fractionated RT. Altered fractionated RT, specifically hyperfractionated, may improve the results. The question is how to weigh hyperfractionated RT vs concurr...
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