How would you treat non-secretory myeloma in an inpatient setting?
Does your management change based on the type of end-organ involvement at the time of diagnosis?
Are there any reports of CNS involvement with non-secretory myeloma?
Answer from: Medical Oncologist at Academic Institution
This entity is rare with the use of free light chain assay. About 2% of all cases are non-secretory. In A Greek study, they were younger, less anemic, and had less often renal dysfunction and less extensive bone marrow infiltration. Presence and extent of bone disease were similar, however, hypercal...
Answer from: Medical Oncologist at Academic Institution
Let me break up the question into the following scenarios as I am assuming the patient is newly diagnosed:
- If the patient is Newly diagnosed Non-secretory myeloma (NDNSMM (no end organ damage), I will consider treatment outpatient with a possibility to bridge him with pulse dexamethasone un...
Comments
Medical Oncologist at Wentworth Douglass Hospital Have you seen patients with myeloma and hyperammon...
Medical Oncologist at Mayo Clinic This has been well described, though the mechanism...