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In a patient with resected ER+ HER2- breast cancer, how do you decide between TC vs ddAC-T for adjuvant chemotherapy?
Do you have a cutoff in terms of tumor size, number of LN, Oncotype score, etc that makes you choose lower vs higher intensity chemo?
Answer from: Medical Oncologist at Academic Institution
I seldom (if ever) use the docetaxel/cyclophosphamide regimen. I find it more toxic than DD-AC-T, so I tend to use the latter once I determine that chemotherapy is indicated. Perhaps a more fundamental question for these patients is which needs or is likely to benefit from chemotherapy. If I have an...
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