In patients with multiple basal cell carcinoma lesions on vismodegib, would you hold vismodegib while delivering radiation therapy to one locally advanced BCC lesion that was not amenable to surgery?

Answer from: Medical Oncologist at Academic Institution

I agree. Based on the recently published paper in JCO (Barker et al., PMID 38630954), vismodegib can be safely administered with radiation therapy for locally advanced BCC. RT + vismodegib yielded high rates of control and progression free survival.

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Radiation Oncologist at Lake Region Healthcare
I would always be sure that such a patient does no...

Answer from: Radiation Oncologist at Academic Institution

No. Barker et al., PMID 38630954

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In patients with multiple basal cell carcinoma lesions on vismodegib, would you hold vismodegib while delivering radiation therapy to one locally advanced BCC lesion that was not amenable to surgery?

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