In what clinical scenarios do you utilize opioids in patients with restless leg syndrome?  

I would say in refractory RLS. I.e., the patient has failed all the options below: Iron supplementation if ferritin <50, Gabapentin/pregabalin, Dopamine agonists, and Non-pharmacological options (like the vibrating pad). * I don't love carbidopa/levodopa for RLS. It very often causes aug...