In what situations would you consider starting zoledronic acid in an adjuvant setting for a woman with T2N0 hormone positive breast cancer?   

Adjuvant bisphosphonates should be considered in older, postmenopausal women or in younger, premenopausal women who are on ovarian suppression. I would check a baseline DEXA scan in this particular woman, and if she has osteopenia or osteoporosis, I would start her on a bisphosphonate. She would be ...