Is post-mastectomy RT recommended for patients who have a local failure after partial breast irradiation?
If the patient has no pathologic risk factors that would ordinarily necessitate PMRT, do you omit it? Does triple negative subtype affect your decision? Does the partial breast modality (EBRT v. brachytherapy) matter?
Answer from: Radiation Oncologist at Academic Institution
In general if a mastectomy was performed for an inbreast local relapse, whether the patient recieved partial or whole breast previously, or even no radiation, I would not offer PMRT unless there were specific risk factors indicating a need such as a diffuse relapase, dermal invasion, extensive lymph...