Is there a role or data to support the use of Capecitabine with radiation to the breast/axilla in a metastatic ER positive breast cancer in the palliative setting?
Pt has progressed on AI and Faslodex. Goal is radiation to axilla as a palliative intent and Capecitabine to control systemic disease.
Answer from: Medical Oncologist at Academic Institution
I have occasionally administered capceitabine concurrent with radiation as a radiosenitizing agent in patients with unresectable chest wall recurrences with reasonably good tolerance. When administered together, I limit the capecitabine to a dose similar to that used in patients receiving concu...