Is there any benefit of anastrozole in addition to fulvestrant and palbociclib in a patient with HR+ metastatic breast cancer?
Answer from: Medical Oncologist at Academic Institution
We don't have comparative data that I am aware of. SWOG S0226 showed an improvement in PFS/OS for 1st line fulvestrant + anastrozole vs anastrozole, particularly for treatment-naive or > 10-year recurrent metastatic disease. Dr. @Mehta (who led S0226) has opened a phase 2 trial using abemaciclib ...
Comments
Medical Oncologist at Joliet Oncology Hematology Associates Fulvestrant maybe preferred over AI in combination...
Medical Oncologist at Florida Cancer Specialists The question posed did not mention line of therapy
Fulvestrant maybe preferred over AI in combination...
The question posed did not mention line of therapy