Int. J. Radiat. Oncol. Biol. Phys.

Carcinoma of the urinary bladder category T3NxMo treated by the combination of radium implant and external irradiation: second report.

Abstract

Forty-one patients with bladder cancer, T3NxMo, with a diameter not exceeding 5 cm, were treated by 3 times 350 rad external irradiation, radium implant at reduced dose, and an additional 3000 rad external irradiation ("Radium 55%"). Survival is excellent where there is a high or medium degree of differentiation without vascular invasion in the biopsy specimen; prognosis is poor if a low degree of differentiation is combined with vascular invasion. The future therapeutic approach will be adapted to this finding.

Related Questions

Would you give full post-operative dose radiation for an undifferentiated high grade pleomorphic sarcoma of the extremity with close surgical margins if the patient had previously received <20Gy preoperatively?

3 Answers

Mednet Member

Radiation Oncology · Emeritus Professor

If the patient stopped at 16Gy preoperatively, I doubt they would accept 60-66 Gy postoperatively. Accordingly, I would follow the patient closely with MRI imaging, CT chest, and physical exam. If they developed local relapse without distant mets, I would deliver 45-50 Gy preoperatively (discussing ...