Mednet Logo

Related Questions

How do you approach a patient with a solitary brain metastasis from small cell lung cancer s/p resection with otherwise limited thoracic disease?

1 Answers

Mednet Member
Mednet Member
Radiation Oncology · Case Western Reserve University

This is rather an uncommon situation but can happen if a patient presents with a synchronous solitary brain metastasis (with or w/o symptom) and undergoes craniotomy and resection only to find out that it is small cell lung cancer. Additional information is needed on the volume of intra-thoracic dis...

Does omission of PCI influence your decision whether to offer consolidative thoracic radiation in ES-SCLC after chemo + immunotherapy?

3
2 Answers

Mednet Member
Mednet Member
Radiation Oncology · Tennessee Oncology

This is one of those stories that has evolved over time with our improvements in technology.EORTC 08993 (the Slotman study) demonstrated both an improvement in the rate of symptomatic brain mets at 1 yr from 40% to 15%, and an improvement in 1 yr OS from 13% to 27%. However, a huge caveat here is th...

Is it acceptable to treat newly diagnosed small cell lung cancer with limited brain metastasis with upfront SRS?

36
12 Answers

Mednet Member
Mednet Member
Radiation Oncology · Yale School of Medicine

First, to be clear, there's not good evidence regarding the role of radiosurgery in small cell patients who have not had WBRT or PCI. In patients without brain metastases, there's a clearly defined and clinically significant survival benefit, which seems to result from both control of existing metas...