Increased Risk of Heart Failure Hospitalization With GLP-1 Receptor Agonists in Patients With Reduced Ejection Fraction: A Meta-Analysis of the EXSCEL and FIGHT Trials.

Journal of cardiac failure 2023 Apr 05

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Would it be reasonable to begin considering GLP1 RAs or finerenone for patients with heart failure with recovered LVEF in light of recent trials such as SELECT and FINEARTS-HF showing some success in HFpEF and HFmrEF populations?

Or should they be continued on maximally tolerated GDMT?

New comment by at Hartford HealthCare Medical Group ( September 14, 2025)

I think heart failure with improved ejection fraction will present a unique set of circumstances in recommendations that will expand our understanding of heart failure physiol...

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