Endocrinology and metabolism clinics of North America 2022 Nov 04
Remission in Ketosis-Prone Diabetes.
ABSTRACT
Heterogeneous forms of Ketosis-prone diabetes (KPD) are characterized by patients who present with diabetic ketoacidosis (DKA) but lack the typical features and biomarkers of autoimmune T1D. The A-β+ subgroup of KPD provides unique insight into the concept of "remission" since these patients have substantial preservation of beta-cell function permitting the discontinuation of insulin therapy, despite initial presentation with DKA. Measurements of C-peptide levels are essential to predict remission and guide potential insulin withdrawal. Further studies into predictors of remission and relapse can help us guide patients with A-β+ KPD toward remission and develop targeted treatments for this form of atypical diabetes.
New comment by at Texas Diabetes And Endocrinology Pa ( March 1, 2025)
Dr. @Asadipooya,
Thank you for the additional information/references. Your comments are very helpful.
Both TZDs and SFUs might be considered for prolonging remission.
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