Many cancers can spread to the liver, often as the sole site of metastatic disease. For properly selected patients with limited hepatic disease and good performance status, an aggressive strategy involving radical local therapy to the site(s) of metastasis offers a chance for extended disease-free survivorship. The development of stereotactic body radiotherapy has inserted radiation therapy into the arsenal of valuable treatment options in this clinical setting. This article summarizes the latest advancements in the use of stereotactic body radiotherapy to treat liver metastases.